Best Erectile Dysfunction drug in the UK

Which Erectile Dysfunction drug is best in the UK?

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Erectile dysfunction (ED) is a common condition affecting millions of men in the UK. It can be caused by various factors, from physical health to psychological well-being.  If you’re experiencing ED, you’re not alone, and there are effective treatment options available.

One of the most popular approaches to address ED is medication. But with a variety of brands and types on the market, choosing the “best” one can feel overwhelming. This blog aims to simplify your decision-making process by providing an overview of the most commonly prescribed erectile dysfunction drugs in the UK, along with a comparison table to guide you.

Understanding How ED Medication Works

ED medications primarily work by increasing blood flow to the penis during sexual stimulation. This allows for a firmer and more sustained erection. Here’s a breakdown of the different types of ED medication available:

  • Phosphodiesterase-5 (PDE5) Inhibitors: This is the most common category of ED medication. It includes drugs like Viagra (Sildenafil), Cialis (Tadalafil), Levitra (Vardenafil), and Spedra (Avanafil). These medications relax the smooth muscles in the penis, allowing for increased blood flow.

  • Alprostadil: This medication comes in a suppository form inserted into the urethra at the tip of the penis. It directly stimulates blood flow to the penis.

Important Note: This information is for general knowledge only and should not be a substitute for professional medical advice. Always consult a healthcare professional before starting any new medication, especially if you have any underlying health conditions.

Choosing the Right Medication for You

The best ED medication depends on your unique needs. Several factors will influence which option is most suitable for you:

  • Frequency of sexual activity: If you plan sexual activity occasionally, medications like Viagra (Sildenafil) or Levitra (Vardenafil) might be suitable. For more frequent encounters, Tadalafil (Cialis) or its daily versions could be an option.
  • Duration of effect: For longer-lasting results, consider Tadalafil (Cialis) or its daily versions.
  • Severity and cause of your ED: Discussing your symptoms with a healthcare professional is crucial to determine the appropriate medication type and dosage.
  • Underlying health conditions: Certain medications may interact with ED drugs. Discuss your medical history with your healthcare professional to ensure safety.
  • Your lifestyle: Consider how quickly you want the medication to take effect and how long you need it to last.
  • Personal preference: Some men might prefer a discreet option like Spedra, while others might be comfortable with a longer-lasting medication like Cialis Daily.

Comparison of Erectile Dysfunction Drugs in the UK:

Here’s a table outlining some key features of popular ED medications available in the UK

Medication 
(Brand & Generic)
Active IngredientDosage (mg)Onset of ActionDuration of ActionAvailability
Viagra (Sildenafil)Sildenafil25, 50, 10030-60 minutes4 hoursTablets
Sildenafil (Generic Viagra)Sildenafil25, 50, 10030-60 minutes4 hoursTablets
Viagra Connect (Sildenafil)Sildenafil50mg only30-60 minutes4 hoursTablets
Tadalafil (Generic Cialis)Tadalafil2.5, 5, 10, 202-4 hoursUp to 36 hoursTablets
Tadalafil Daily (Generic Cialis Daily)Tadalafil2.5, 5Not applicable (daily use)Up to 36 hoursTablets
Cialis (Tadalafil)Tadalafil2.5, 5, 10, 202-4 hoursUp to 36 hoursTablets
Cialis Daily (Tadalafil Daily)Tadalafil2.5, 5Not applicable (daily use)Up to 36 hoursTablets
Vardenafil (Generic Levitra)Vardenafil5, 10, 2060 minutesUp to 5 hoursTablets
Levitra (Vardenafil)Vardenafil5, 10, 2060 minutesUp to 5 hoursTablets
Spedra (Avanafil)Avanafil50, 100, 20015-30 minutes4-5 hoursTablets

Viagra (Sildenafil) and Sildenafil (Generic Viagra):  A popular choice known for its effectiveness. Onset of action takes around 30-60 minutes, and it lasts for about 4 hours.

Viagra Connect (Sildenafil): A convenient option for occasional use. 

Tadalafil (Cialis) and Tadalafil Daily (Cialis Daily):  Offers a longer duration of action (up to 36 hours) compared to Viagra.  The “weekend pill” option (taken as needed) is ideal for spontaneous encounters.  The daily version provides low-level, continuous effectiveness.

Vardenafil (Levitra):  Similar to Viagra in terms of onset and duration.

Spedra (Avanafil):  The fastest-acting ED medication, taking effect within 15-30 minutes.  Ideal for those who prefer a spontaneous approach.

Branded and generic ED medications often contain the exact same active ingredient. For example  Viagra (a branded ED treatment) and Sildenafil (generic Viagra) for example – both have Sildenafil. This means generic ED meds offer the same medical benefits as their branded counterparts and are equally effective.

Important Considerations Before Taking ED Medication

  • Consult a Healthcare professional: It’s vital to discuss your ED with a clinician before taking any medication. They can diagnose the underlying cause and recommend the safest and most effective treatment for you.
  • Be Transparent: Disclose all your medical history and current medications to your healthcare professional to avoid any potential interactions.
  • Realistic Expectations: ED medication is not an aphrodisiac. It enhances your response to sexual stimulation, but it won’t create desire on its own.
  • Lifestyle factors: Maintaining a healthy weight, exercising regularly, and managing stress can all contribute to improved erectile function.
  • Psychological aspects: ED can sometimes have a psychological component. Talking to a therapist alongside medication could be beneficial.
  • Potential Side Effects: Like all medications, ED drugs can cause side effects, such as headache, flushing, and indigestion. These are usually mild and temporary. However, it’s important to be aware of them and discuss any concerns with your clinician.

Key Takeaway

The best ED medication will vary depending on individual needs and preferences. Discuss your lifestyle and expectations with your healthcare professional to determine. Consultation is key which will help to assess your underlying health, potential drug interactions, and recommend the most suitable option.

References

  • Carson, C. C. and Lue, T. F. (2005) “Phosphodiesterase type 5 inhibitors for erectile dysfunction,” BJU international, 96(3), pp. 257–280. doi: 10.1111/j.1464-410x.2005.05614.x.

  • Coward, R. and Carson, C. (2008) “Tadalafil in the treatment of erectile dysfunction,” Therapeutics and clinical risk management, 4(6), pp. 1315–1329. doi: 10.2147/tcrm.s3336.

  • Essential information for the supply of Viagra connect (2022) Org.uk. Available at: https://www.medicines.org.uk/emc/rmm/1784/Document.

  • Goldstein, I. et al. (1998) “Oral sildenafil in the treatment of erectile dysfunction,” The New England journal of medicine, 338(20), pp. 1397–1404. doi: 10.1056/nejm199805143382001.

  • Gong, B. et al. (2017) “Direct comparison of tadalafil with sildenafil for the treatment of erectile dysfunction: a systematic review and meta-analysis,” International urology and nephrology, 49(10), pp. 1731–1740. doi: 10.1007/s11255-017-1644-5.

  • “Key points from the evidence | Erectile dysfunction: avanafil | Advice | NICE” (no date). Available at: https://www.nice.org.uk/advice/esnm45/chapter/Key-points-from-the-evidence. 

  • Langtry, H. D. and Markham, A. (1999) “Sildenafil: A Review of its Use in Erectile Dysfunction,” Drugs, 57(6), pp. 967–989. doi: 10.2165/00003495-199957060-00015.

  • Tsertsvadze, A. et al. (2009) Oral phosphodiesterase-5 inhibitors and hormonal treatments for erectile dysfunction: a systematic review and meta-analysis. Centre for Reviews and Dissemination.

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